Mapping the binding site for the GTP-binding protein Rac-1 on its inhibitor RhoGDI-1
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چکیده
منابع مشابه
Interaction of Nck-associated protein 1 with activated GTP-binding protein Rac.
Bacterially expressed glutathione S-transferase fusion proteins containing Rac1 were used to identify binding proteins of this Rho family GTPase present in a bovine brain extract. Five proteins of 85, 110, 125, 140 and 170 kDa were detected, all of which were associated exclusively with guanosine 5'-[gamma-thio]triphosphate-bound Rac1, not with GDP-bound Rac1. The 85 and 110 kDa proteins were i...
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ژورنال
عنوان ژورنال: Structure
سال: 2000
ISSN: 0969-2126
DOI: 10.1016/s0969-2126(00)00080-0